Supportive references from the literature


Topic 1

Innate antibodies (B-1A cells, sIgM, natural Abs & innate immunity to CoV and Covid-19)

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7202830/

doi: https://doi.org/10.1016/S2352-4642(20)30135-8

https://www.frontiersin.org/articles/10.3389/fimmu.2020.02139/full

doi: https://doi.org/10.3389/fimmu.2020.02139

https://www.nature.com/articles/s41385-020-00359-2

doi: https://doi.org/10.1038/s41385-020-00359-2

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5526850/

doi: https://doi.org/10.3389/fimmu.2017.00872

https://www.frontiersin.org/articles/10.3389/fimmu.2020.595535/full

doi: https://doi.org/10.3389/fimmu.2020.595535

https://journals.lww.com/shockjournal/fulltext/2020/11000/therapeutic_potential_of_b_1a_cells_in_covid_19.2.aspx

doi: https://10.1097/SHK.0000000000001610

https://www.frontiersin.org/articles/10.3389/fphar.2020.01309/full

doi: https://doi.org/10.3389/fphar.2020.01309

https://pubmed.ncbi.nlm.nih.gov/23692567/

doi: https://doi.org/10.1111/nyas.12137  

https://pubmed.ncbi.nlm.nih.gov/20948548/

doi : https://doi.org/10.1038/nri2849

https://www.sciencedirect.com/science/article/pii/S1939455120303793

doi: https://doi.org/10.1016/j.waojou.2020.100476

https://www.frontiersin.org/articles/10.3389/fimmu.2019.00483/full

doi: https://doi.org/10.3389/fimmu.2019.00483

https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC4703052/

doi: https://doi.org/10.1093/emph/eov033

https://rupress.org/jem/article/188/12/2381/7680/A-Critical-Role-of-Natural-Immunoglobulin-M-in

doi: https://doi.org/10.1084/jem.188.12.2381

https://www.sciencedirect.com/science/article/abs/pii/S0952791519300779

doi: https://doi.org/10.1016/j.coi.2019.09.003

https://link.springer.com/article/10.1007%2Fs00281-004-0182-2

doi: https://doi.org/10.1007/s00281-004-0182-2

https://www.frontiersin.org/articles/10.3389/fimmu.2017.01795/full

doi: https://doi.org/10.3389/fimmu.2017.01795

https://www.termedia.pl/Natural-antibodies-facts-known-and-unknown,10,34697,1,1.html

doi: https://doi.org/10.5114/ceji.2018.81354

Topic 2

- Role of natural Abs and NK cells in asymptomatic carriers;

- Substantial transmission by asymptomatically infected subjects;

- Protection of asymptomatic carriers not due to Abs;

https://www.nature.com/articles/s41423-021-00825-2

https://www.medrxiv.org/content/10.1101/2020.12.18.20248447v1

doi : https://doi.org/10.1101/2020.12.18.20248447

https://pubmed.ncbi.nlm.nih.gov/33391280/

doi : https://doi.org/10.3389/fimmu.2020.610300

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7608887/

doi : https://doi.org/10.1371/journal.pone.0241536


https://www.nature.com/articles/s41392-021-00525-3

​​

Topic 3

- Natural Abs facilitate MHC class I-restricted antigen presentation;

- Conserved, CoV-associated cell surface-expressed MHC cl. I peptides ;

https://www.nature.com/articles/nm933

doi: https://10.1038/nm933

https://pubmed.ncbi.nlm.nih.gov/19439480/

doi : https://10.1128/JVI.00079-09


Topic 4

- Abs may bind to Sars-CoV-2 without neutralizing the virus / preventing infection​

https://www.pennmedicine.org/news/news-releases/2021/february/antibodies-to-common-cold-coronaviruses-do-not-protect-against-sars-cov2

Topic 5

Natural and vaccine-induced immune escape

- The predominance of immune-evading variants among post-vaccination cases indicates possible selective pressure for antibody-resistant escape variants circulating locally over time in the vaccinated population. Our data suggest that vaccination at levels below the threshold for achieving herd immunity may increase selection for antibody-resistant variants - https://innovativegenomics.org/wp-content/uploads/2022/01/Servellita-2022.pdf

- Antigenic escape selects for the evolution of higher pathogen transmission and virulence - https://www.nature.com/articles/s41559-021-01603-z

- Emerging Vaccine-Breakthrough SARS-CoV‑2 Variants - https://pubs.acs.org/doi/pdf/10.1021/acsinfecdis.1c00557

- Mechanisms of SARS-CoV-2 Evolution Revealing Vaccine-Resistant Mutations in Europe and America - Publication Here

- Unifying the Epidemiological and Evolutionary Dynamics of Pathogens - Publication Here

doi: https://doi.org/10.1126/science.1090727

​- Emergence of immune escape at dominant SARS-CoV-2 killer T-cell epitope - Publication Here

doi: https://doi.org/10.1101/2021.06.21.21259010

- The emergence and ongoing convergent evolution of the N501Y lineages coincides with a major global shift in the SARS-CoV-2 selective landscape https://pubmed.ncbi.nlm.nih.gov/33688681/
- Risk of rapid evolutionary escape from biomedical interventions targeting SARS-CoV-2 spike protein https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0250780
- SARS-CoV-2 variants, spike mutations and immune escape https://www.nature.com/articles/s41579-021-00573-0.pdf
- Vaccination and the dynamics of immune evasion https://pubmed.ncbi.nlm.nih.gov/17210532/

https://www.cell.com/cell/fulltext/S0092-8674(21)00226-9?

doi: https://doi.org/10.1016/j.cell.2021.02.037

https://www.biorxiv.org/content/10.1101/2020.12.28.424451v1

doi : https://doi.org/10.1101/2020.12.28.424451

https://science.sciencemag.org/content/371/6527/329
doi: https://10.1126/science.371.6527.329

https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.1002198

doi: https://doi.org/10.1371/journal.pbio.1002198

https://www.thelancet.com/journals/lanpub/article/PIIS2468-2667(21)00036-0/fulltext

doi: https://doi.org/10.1016/S2468-2667(21)00036-0

https://www.nature.com/articles/d41586-021-00121-z

https://science.sciencemag.org/content/371/6526/284

https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(21)00183-5/fulltext

doi: https://doi.org/10.1016/S0140-6736(21)00183-5

https://immunology.sciencemag.org/content/6/57/eabg6461

https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(21)00468-2/fulltext?fbclid=IwAR1K_tzlvBP4_yJ95jnpsj0yBxqjClZrcEQDemR5xMA64HopMZMmSV1JkKw

doi: https://doi.org/10.1016/S0140-6736(21)00468-2

https://www.sciencedirect.com/science/article/pii/S0092867421003676?via%3Dihub

https://www.karger.com/Article/FullText/515417

doi: https://doi.org/10.1159/000515417

https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(21)00148-1/fulltext

doi: https://doi.org/10.1016/j.ebiom.2021.103355

https://www.medrxiv.org/content/10.1101/2021.04.06.21254882v2

doi: https://doi.org/10.1101/2021.04.06.21254882

Topic 6

Mechanism of viral shedding and clearance

https://www.thelancet.com/journals/lanmic/article/PIIS2666-5247(20)30172-5/fulltext

doi: https://doi.org/10.1016/S2666-5247(20)30172-5


Topic 7

Dynamics of humoral anti-Covid-19 immune response and potential for reinfection

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7641391/

doi : https://doi.org/10.1099/jgv.0.001439


Topic 8

Lessons learned from Smallpox vaccines and Influenza pandemic 1918

https://pubmed.ncbi.nlm.nih.gov/20860482/

doi: https://10.2217/fmb.10.98

https://www.cnbc.com/2020/09/28/comparing-1918-flu-vs-coronavirus.html

https://www.smithsonianmag.com/science-nature/compare-flu-pandemic-1918-and-covid-19-caution-180975040/

https://theconversation.com/what-makes-a-wave-of-disease-an-epidemiologist-explains-141573

Topic 9

Re-exposure to S protein in subjects previously primed by natural infection elicits cross-variant neutralizing antibodies

mRNA vaccination boosts cross-variant neutralizing antibodies elicited by SARS-CoV-2 infection (Science)

Topic 10:

Influenza pandemic 1918: observations and data collected from autopsy samples indicate that no new variants occurred

1918 Influenza Pandemic Caused by Highly Conserved Viruses with Two Receptor-Binding Variants

1918 Influenza: the Mother of All Pandemics

Topic 11:

Children Vaccination

Feature: Thescientific case for an immediate halt to covid ‘vaccination’ of children

De wetenschappelijke argumenten voor eenonmiddellijke stopzetting van covid ‘vaccinatie’ bijkinderen


Topic 1

Innate antibodies (B-1A cells, sIgM, natural Abs & innate immunity to CoV and Covid-19)

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7202830/

doi: https://doi.org/10.1016/S2352-4642(20)30135-8

https://www.frontiersin.org/articles/10.3389/fimmu.2020.02139/full

doi: https://doi.org/10.3389/fimmu.2020.02139

https://www.nature.com/articles/s41385-020-00359-2

doi: https://doi.org/10.1038/s41385-020-00359-2

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5526850/

doi: https://doi.org/10.3389/fimmu.2017.00872

https://www.frontiersin.org/articles/10.3389/fimmu.2020.595535/full

doi: https://doi.org/10.3389/fimmu.2020.595535

https://journals.lww.com/shockjournal/fulltext/2020/11000/therapeutic_potential_of_b_1a_cells_in_covid_19.2.aspx

doi: https://10.1097/SHK.0000000000001610

https://www.frontiersin.org/articles/10.3389/fphar.2020.01309/full

doi: https://doi.org/10.3389/fphar.2020.01309

https://pubmed.ncbi.nlm.nih.gov/23692567/

doi: https://doi.org/10.1111/nyas.12137  

https://pubmed.ncbi.nlm.nih.gov/20948548/

doi : https://doi.org/10.1038/nri2849

https://www.sciencedirect.com/science/article/pii/S1939455120303793

doi: https://doi.org/10.1016/j.waojou.2020.100476

https://www.frontiersin.org/articles/10.3389/fimmu.2019.00483/full

doi: https://doi.org/10.3389/fimmu.2019.00483

https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC4703052/

doi: https://doi.org/10.1093/emph/eov033

https://rupress.org/jem/article/188/12/2381/7680/A-Critical-Role-of-Natural-Immunoglobulin-M-in

doi: https://doi.org/10.1084/jem.188.12.2381

https://www.sciencedirect.com/science/article/abs/pii/S0952791519300779

doi: https://doi.org/10.1016/j.coi.2019.09.003

https://link.springer.com/article/10.1007%2Fs00281-004-0182-2

doi: https://doi.org/10.1007/s00281-004-0182-2

https://www.frontiersin.org/articles/10.3389/fimmu.2017.01795/full

doi: https://doi.org/10.3389/fimmu.2017.01795

https://www.termedia.pl/Natural-antibodies-facts-known-and-unknown,10,34697,1,1.html

doi: https://doi.org/10.5114/ceji.2018.81354

Topic 2

- Role of natural Abs and NK cells in asymptomatic carriers;

- Substantial transmission by asymptomatically infected subjects;

- Protection of asymptomatic carriers not due to Abs;

https://www.medrxiv.org/content/10.1101/2020.12.18.20248447v1

doi : https://doi.org/10.1101/2020.12.18.20248447

https://pubmed.ncbi.nlm.nih.gov/33391280/

doi : https://doi.org/10.3389/fimmu.2020.610300

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7608887/

doi : https://doi.org/10.1371/journal.pone.0241536


https://www.nature.com/articles/s41392-021-00525-3

​​

Topic 3

- Natural Abs facilitate MHC class I-restricted antigen presentation;

- Conserved, CoV-associated cell surface-expressed MHC cl. I peptides ;

https://www.nature.com/articles/nm933

doi: https://10.1038/nm933

https://pubmed.ncbi.nlm.nih.gov/19439480/

doi : https://10.1128/JVI.00079-09


Topic 4

- Abs may bind to Sars-CoV-2 without neutralizing the virus / preventing infection​

https://www.pennmedicine.org/news/news-releases/2021/february/antibodies-to-common-cold-coronaviruses-do-not-protect-against-sars-cov2

Topic 5

Natural and vaccine-induced immune escape

- Emerging Vaccine-Breakthrough SARS-CoV‑2 Variants - https://pubs.acs.org/doi/pdf/10.1021/acsinfecdis.1c00557

- Mechanisms of SARS-CoV-2 Evolution Revealing Vaccine-Resistant Mutations in Europe and America - Publication Here

- Unifying the Epidemiological and Evolutionary Dynamics of Pathogens - Publication Here

doi: https://doi.org/10.1126/science.1090727

​- Emergence of immune escape at dominant SARS-CoV-2 killer T-cell epitope - Publication Here

doi: https://doi.org/10.1101/2021.06.21.21259010

- The emergence and ongoing convergent evolution of the N501Y lineages coincides with a major global shift in the SARS-CoV-2 selective landscape https://pubmed.ncbi.nlm.nih.gov/33688681/
- Risk of rapid evolutionary escape from biomedical interventions targeting SARS-CoV-2 spike protein https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0250780
- SARS-CoV-2 variants, spike mutations and immune escape https://www.nature.com/articles/s41579-021-00573-0.pdf
- Vaccination and the dynamics of immune evasion https://pubmed.ncbi.nlm.nih.gov/17210532/

https://www.cell.com/cell/fulltext/S0092-8674(21)00226-9?

doi: https://doi.org/10.1016/j.cell.2021.02.037

https://www.biorxiv.org/content/10.1101/2020.12.28.424451v1

doi : https://doi.org/10.1101/2020.12.28.424451

https://science.sciencemag.org/content/371/6527/329
doi: https://10.1126/science.371.6527.329

https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.1002198

doi: https://doi.org/10.1371/journal.pbio.1002198

https://www.thelancet.com/journals/lanpub/article/PIIS2468-2667(21)00036-0/fulltext

doi: https://doi.org/10.1016/S2468-2667(21)00036-0

https://www.nature.com/articles/d41586-021-00121-z

https://science.sciencemag.org/content/371/6526/284

https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(21)00183-5/fulltext

doi: https://doi.org/10.1016/S0140-6736(21)00183-5

https://immunology.sciencemag.org/content/6/57/eabg6461

https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(21)00468-2/fulltext?fbclid=IwAR1K_tzlvBP4_yJ95jnpsj0yBxqjClZrcEQDemR5xMA64HopMZMmSV1JkKw

doi: https://doi.org/10.1016/S0140-6736(21)00468-2

https://www.sciencedirect.com/science/article/pii/S0092867421003676?via%3Dihub

https://www.karger.com/Article/FullText/515417

doi: https://doi.org/10.1159/000515417

https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(21)00148-1/fulltext

doi: https://doi.org/10.1016/j.ebiom.2021.103355

https://www.medrxiv.org/content/10.1101/2021.04.06.21254882v2

doi: https://doi.org/10.1101/2021.04.06.21254882

Topic 6

Mechanism of viral shedding and clearance

https://www.thelancet.com/journals/lanmic/article/PIIS2666-5247(20)30172-5/fulltext

doi: https://doi.org/10.1016/S2666-5247(20)30172-5


Topic 7

Dynamics of humoral anti-Covid-19 immune response and potential for reinfection

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7641391/

doi : https://doi.org/10.1099/jgv.0.001439


Topic 8

Lessons learned from Smallpox vaccines and Influenza pandemic 1918

https://pubmed.ncbi.nlm.nih.gov/20860482/

doi: https://10.2217/fmb.10.98

https://www.cnbc.com/2020/09/28/comparing-1918-flu-vs-coronavirus.html

https://www.smithsonianmag.com/science-nature/compare-flu-pandemic-1918-and-covid-19-caution-180975040/

https://theconversation.com/what-makes-a-wave-of-disease-an-epidemiologist-explains-141573

Topic 9

Re-exposure to S protein in subjects previously primed by natural infection elicits cross-variant neutralizing antibodies

mRNA vaccination boosts cross-variant neutralizing antibodies elicited by SARS-CoV-2 infection (Science)

Topic 10:

Influenza pandemic 1918: observations and data collected from autopsy samples indicate that no new variants occurred

1918 Influenza Pandemic Caused by Highly Conserved Viruses with Two Receptor-Binding Variants

1918 Influenza: the Mother of All Pandemics

Topic 11:

Children Vaccination

Feature: Thescientific case for an immediate halt to covid ‘vaccination’ of children

De wetenschappelijke argumenten voor eenonmiddellijke stopzetting van covid ‘vaccinatie’ bijkinderen

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