November 2, 2022

VSS Scientific Updates During Pandemic Times #43

1.    High Pathogenicity AvianInfluenza (HPAI)- Situation Report 33

From Geert: “Avian Flu is yet another Sword of Damocles hanging over highly C-19 vaccinated populations. I’ve repeatedly explained how highly C-19 vaccinated populations are likely to contribute to asymptomatic human-to-human transmission of avian influenza and hence are prone to enable enhanced infection rates and immune escape into variants that are more transmissible among humans. Also, given the current threat from avian Flu, it is critical that people do not vaccinate against seasonal Flu as Abs induced against common Influenza strains are at high risk of provoking Ab-dependent enhancement of disease upon exposure to avian Flu!!”

2.    Role of Spike in the Pathogenicand Antigenic Behavior of SARS-CoV-2 BA.1 Omicron

From Geert: “Only read the abstract so far, but it seems a simplistic conclusion as theSARS-CoV-2 ‘background’ shapes conformation of S and conformation is critical for viral entry, fusogenicity and induction of infection-enhancing Abs. The cut-and-paste approach is, therefore, simplistic and does not take into consideration allosteric changes induced by the foreign background. Those changes are likely to profoundly impact the biophysical and biological behavior of S protein, irrespective of the latter’s origin!”

3.    Unvaccinated Children Are ‘Our Only Hope’ in Generating Herd Immunity: Vaccine Expert

“The children are our only hope still, to generate herd immunity,” Vanden Bossche told The Epoch Times. “And herd immunity means, thanks to their natural immunity, they can kill the virus, they can sterilize the virus.”

4.    Endonuclease Fingerprint Indicates a Synthetic Origin of SARS-CoV-2

“The genome of SARS-COV-2 contains a peculiar pattern of unique restriction endonuclease recognition sites allowing efficient dis- and re-assembly of the viral genome characteristic of synthetic viruses. Here, we report the likelihood of observing such a pattern in coronaviruses with no history of bioengineering. We find that SARS-CoV-2 is an anomaly, more likely a product of synthetic genome assembly than natural evolution.”

5.    Cases of BQ.1, BQ.1.1 COVID Variants Double in U.S. as Europe Warns of Rise

“ regulators on Friday estimated that BQ.1 and closely related BQ.1.1accounted for 16.6% of coronavirus variants in the country, nearly doubling from last week, while Europe expects them to become the dominant variants in a month.”

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Geert Vanden Bossche received his DVM from the University of Ghent, Belgium, and his PhD degree in Virology from the University of Hohenheim, Germany. He held adjunct faculty appointments at universities in Belgium and Germany. After his career in Academia, Geert joined several vaccine companies (GSK Biologicals, Novartis Vaccines, Solvay Biologicals) to serve various roles in vaccine R&D as well as in late vaccine development.

Geert then moved on to join the Bill & Melinda Gates Foundation’s Global Health Discovery team in Seattle (USA) as Senior Program Officer; he then worked with the Global Alliance for Vaccines and Immunization (GAVI) in Geneva as Senior Ebola Program Manager. At GAVI he tracked efforts to develop an Ebola vaccine. He also represented GAVI in fora with other partners, including WHO, to review progress on the fight against Ebola and to build plans for global pandemic preparedness.

Back in 2015, Geert scrutinized and questioned the safety of the Ebola vaccine that was used in ring vaccination trials conducted by WHO in Guinea. His critical scientific analysis and report on the data published by WHO in the Lancet in 2015 was sent to all international health and regulatory authorities involved in the Ebola vaccination program. After working for GAVI, Geert joined the German Center for Infection Research in Cologne as Head of the Vaccine Development Office. He is at present primarily serving as a Biotech / Vaccine consultant while also conducting his own research on Natural Killer cell-based vaccines.


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