Omicron Causes Enhanced Large-Scale Immune Escape Dynamics.…
Summary of the key messages: Immune refocusing is the key to immune escape and collateral non-SARS-CoV-2 disease.…
Mass vaccination generated an immune escape landscape where vaccine breakthrough infections enabled Omicron to resist the neutralizing capacity of antibodies, leading to an overall weakened immune response, thereby further enhancing viral immune escape…
Q&A #22 : about the origin of dominant immune escape SARS-CoV-2 variants. By. Geert Vanden Bossche. Question: How could I be so wrong as to pretend that mass vaccination is responsible for immune escape of more infectious SARS-CoV-2 variants?…
The inescapable immune escape pandemic. By. Geert Vanden Bossche. How will the ongoing immune escape pandemic end?…
Scientists continue to disregard Darwin's theory and incorrectly and vaguely attribute ‘immune suppression’(!) as the cause of the chronic shedding of evolving SARS-CoV-2 immune escape variants during this 'chronic phase' of the pandemic.…
The inescapable immune escape pandemic. ’, mRNA vaccines elicit such broadly NAbs even in the absence of VBTIs).…
How mRNA Vaccines and Vaccine Breakthrough Infections Drive Viral Immune Escape Dynamics. The development of herd immunity to COVID-19 has been hindered by mRNA vaccines and vaccine breakthrough infections of new Omicron variants.…
Trained-Cell-Based Innate Immunity: How It Protects the Unvaccinated from Covid19 Escape Variants.…
Geert Vanden Bossche PhD and his warning to the world against 'Immune Escape'. Geert Vanden Bossche PhD, DVM is an internationally recognised expert in vaccine development.…
Here’s a summary of my comments: ‘Antigenically broad immune responses’ alone do not guarantee protection against newly emerging immune escape variants.…
As the mass vaccination campaigns were conducted in the midst of a pandemic, they predictably led to the selection of more infectious immune escape variants that managed to overcome the suboptimal vaccine-induced immunity and therefore spectacularly increased…
Only Trained Cellular Innate Immunity Yields Durable Protection During An Immune Escape Pandemic.…
It is well known that vaccines promoting immune responsiveness to a more diverse spectrum of pathogen variants may drive large-scale immune escape if the functional capacity of the induced immune effector cells is suboptimal, meaning they are unable to…
As large-scale suboptimal humoral immune pressure on viral infectiousness drives natural selection and expansion of immune escape variants that the C-19 vaccine-induced antibodies (Abs) cannot sufficiently neutralize, infection-enhancing polyreactive,…
What all of them missed is that mRNA vaccines or. breakthrough infections due to Omicron immune escape variants in previously C-19 vaccinated people. (even with non-mRNA vaccines) lead to something called ‘immune refocusing’.…
The Inescapable Immune Escape Pandemic. By. Geert Vanden Bossche. Nobody Can Conceal The Science That Nature Is Now Desperate To Unveil. Society in highly vaccinated countries will be caught by surprise.…
That type of immunity is not prone to immune escape since abrogation of viral infection is based on elimination of virus-infected host cells by MHC-unrestricted, polyspecific T cells.…
However, much less progress has been made in our fundamental understanding of host-pathogen interactions and immune subversive mechanisms which pathogenic agents have evolved to escape natural mechanisms of host immune defence.…
everyone understands that the interplay between the virus/pathogen and the host population's immunity is complex and constantly determined by the pressure exerted by the population's adaptive immunity on the virus and the virus's adaptation to the changing immune…
Earlier this week, his book "The Inescapable Immune Escape Pandemic" was published.…
Our first discussion highlighted the risk of viral "immune escape" when using a prophylactic vaccine during a pandemic. This is a follow up interview to discuss some outstanding issues.…
Geert Vanden Bossche Warns the Vaccinated of Immune Escape Variants. Support our work. DONATE. Follow us on. Subscribe to our Newsletter. Voice For Science and Solidarity. by Geert Vanden Bossche. Sitemap. Home. Mission. Team. Contributors. Blog.…
This at least would reflect the increasing trend of convergence of immune escape mutations to a limited set of Sars-CoV-2 S protein-associated epitopes.…
-vanden-bossches-analysis-of-the-covid-19-immune-escape-pandemic-6007d78d. ].…
Think about the evolutionary logic and you will comprehend the outcome of this immune escape pandemic…. By. Geert Vanden Bossche.…
This will drive natural selection of more infectious immune escape variants that will eventually adapt to the population because they’ve gained a competitive replication advantage. When that happens, the variant becomes dominant.…
However, vaccinated people are far more prone to breeding viral immune escape variants than non-vaccinated naturally infected individuals. Why?…
These esteemed scientists seem unaware that what they are looking at in their in vitro neutralization assays are ‘pseudo’neutralizing antibodies (Abs) that merely accelerate viral immune escape.…
antibodies against spike (S) protein that is expressed on the surface of transfected host cells* (this is something which clearly does not occur during natural infection of host cells with SARS-CoV-2 as I extensively explain in my book: "The inescapable immune…
drives immune escape, first away from the recalled broadly neutralizing (i.e. variant-nonspecific) Abs and subsequently from the broadly infection-inhibiting Abs.…
As breakthrough infections accumulate, immune escape variants will only become more and more prevalent.…
Brad Miller (IPAK-EDU LLC) Interviews Geert Vanden Bossche on The Immune Biology of Natural and Immune Escape Pandemics/Epidemics. Support our work. DONATE. Follow us on. Subscribe to our Newsletter.…
(https://bit.ly/3NYokkE), mRNA vaccines lead to immune refocusing, where suboptimal Abs are induced. against immune subdominant or immune-recessive epitopes on the S protein.…
Reflections on the ongoing immune escape pandemic. By. Geert Vanden Bossche. The quieter it gets around the acute cases of Covid-19, the more worried I become.…
('The Inescapable Immune Escape Pandemic'), this protection is most likely due to the virulence-inhibiting effect of polyreactive non-neutralizing antibodies (PNNAbs)1, and not to 'rapid T cell memory'.…
I read the following contribution from Milton Simba Kambarami: https://medium.com/microbial-instincts/pirola-covid-variant-has-evolved-again-showing-enhanced-immune-escape-3b37d94196d1.…
With more people getting vaccinated against COVID-19, it is important to know that the virus more readily adapts, selecting variants capable of breaking through suboptimal vaccine-mediated immune pressure.…
Natural and vaccine-induced immune escape. - The predominance of immune-evading variants among post-vaccination cases indicates possible selective pressure for antibody-resistant escape variants circulating locally over time in the vaccinated population…
refocusing and eventually led to a diversified spectrum of more infectious immune escape variants.…
Is the bird flu panzootic expediting the end of the SARS-CoV-2 immune escape pandemic? SUMMARY.…
and adaptation of new immune escape variants. that enable an even higher infectiousness.…
The immune biology of natural and immune escape pandemics/epidemics - UPDATED! By. Geert Vanden Bossche.…
For those who have followed my insights and predictions regarding the endpoint of the ongoing immune escape pandemic, this precisely explains how mass vaccination against SARS-CoV-2 during the pandemic has actually benefited the virus's adaptation, rather…
various scientific disciplines before one truly grasps the remarkable level of sophistication with which Nature restores disrupted equilibriums/balances, such as those occurring between an infectious pathogen and population-level immunity during an immune…
Re-exposure to the virus or a vaccine booster may initially sustain protection, but not without increasing immune selection pressure on viral pathogenicity.…
Vaccination of young children will only simulate the effect of infection-enhancing Abs blowing through the innate immune system, even before new circulating immune escape variants enable ADED in the remainder of the vaccinated population.…
escape variants, thereby enabling them to reproduce more effectively.…
co-circulation of a diversified array/spectrum of increasingly infectious “immune escape” variants.…
Geert Vanden Bossche's new book, 'The Inescapable Immune Escape Pandemic -- Nobody Can Conceal The Science That Nature Is Now Desperate to Unveil -- Societies in Highly Vaccinated Countries Will Be Caught By Surprise.'. Support our work. DONATE.…
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